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At therapeutic IV concentrations, it modulates NMDA receptors in the brain, which reduces the calcium influx that drives migraine aura and cortical spreading depression
For further understanding of the underlying mechanisms, analysis of tissues and fluids for OTA and the known metabolites could be a promising next step
After rapid mixing, the light absorption A1 and A2 of 30 s and 150 s respectively were measured at 412 nm, A= A2- A1
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