Regarding the mechanisms of crossing the nasopharyngeal barrier, a combination of transcellular and paracellular pathways seems possible if meningococci using the transcellular pathway induce a sufficient level of inflammation to alter epithelial permeability, allowing other meningococci to follow the paracellular pathway
Insiska-RakMSikorskiMWolnicka-GlubiszA
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Zhou J, Cai X, Huang X, Dai Y, Sun L, Zhang B, et al
To investigate the transcriptomic changes induced by Gclc deletion, we performed downstream analyses of FoB (Supplementary Fig