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Sermorelin is Category 1 eligible for compounding under 503A regulations and can be legally prescribed and compounded
However, the clinical utility of native GLP-1 is limited due to its extremely short half-life (only a few minutes), as it is rapidly degraded by the enzyme dipeptidyl peptidase-4 (DPP-4)
Lucas C, Salesse L, Hoang MHT, Bonnet M, Sauvanet P, Larabi A, et al
10.3389/fphar.2020.00645 Front Pharmacol
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