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Excessive NMDA receptor activation triggers Ca 2+ influx, leading to mitochondrial dysfunction and OS, ultimately resulting in the death of neurons due to excitotoxicity [21]
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Multiple protein families, including ZRT/IRT-related protein (ZIP), HMA, and MTP, contribute to Zn transportation and regulation (Ricachenevsky et al., 2015), which is further elaborated in Table 2
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