Integrates neural recovery and hormonal restoration cycles: Deep sleep is associated with synaptic recalibration, memory consolidation, and hormonal pulse synchronization
Ziegler CGK, Allon SJ, Nyquist SK, Zhang K et al (2020) SARS-CoV-2 Receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues
Microglia are initially activated to stage 1 DAM, which are characterized by a downregulation of homeostatic microglial genes including p2ry12 and cx3cr1 , and an upregulation of genes including trem2 , tyrobp and apoe
Increased resting cerebrovascular tone in individuals along the ADRD progression spectrum (Yew and Nation, 2017) is likely to restrict transient increases in blood pressure into the cerebral circulation
Without baseline data, it is impossible to determine whether a peptide is actually helping or whether natural disease fluctuation is responsible for any changes you observe