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Abstract Purpose of Review Although Glucagon-like peptide (GLP)-1 receptor agonists have been used for almost two decades in the treatment of diabetes mellitus type 2 and, lately, in obesity, recent years have seen an increasing interest in the pharmacological agonism of other proglucagon-derived peptides, including GLP-2

Notably, at higher doses, weight loss appeared to be continuing at week 48 without a clear plateau

Metabolic and Blood Sugar Changes GLP-1 medications can help lower blood sugar through effects on insulin secretion, glucagon signaling, appetite, and food intake

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