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It's important to note that in the UK, weight management medications like Wegovy and Saxenda are typically initiated within specialist weight management services following NICE criteria
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Understanding the mechanism of semaglutide is critical to appreciating its role in weight loss
The activation of the epidermal growth factor receptor (EGFR) signaling pathway has been shown to inhibit the formation of autophagosomes, which are mediated by beclin-1 and LC3B
However, the studies are often short in duration, involve small sample sizes, or use inconsistent outcome measures, making it difficult to draw firm conclusions
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