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10.1136/bmj-2022-071675 53 Hjorth-HansenA.SalvesenO.EngenH
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PMID 21295087
It was showed that NP4 treatment leaded to an increase in pro-inflammatory M1-type macrophages and a decrease in anti-inflammatory M2-type macrophages in mouse tumor tissues, with the proportion of M1 to M2 macrophages being 4.4 times higher compared to untreated mouse tumor tissues (Fig
Another study demonstrated that NAMPT inhibition combined with NAR supplementation resulted in reduced NMN levels and SARM activity, and delayed axon degeneration 290
