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The effects of gut-derived GLP-1 secretion are considered to be more significant in preventing weight gain rather than directly inducing weight loss, based on findings from animal studies on GLP-1 releasers including gastrointestinal distention [53] and d-allulose [54]
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Chiriac et al
8 Second, using a self-administered, off-label, weekly injection with highly specific storage requirements in a condition with potential cognitive impairment created logistical issues that required frequent re-education, management, and surveillance by our team, particularly given his sensitivity to even brief nonadherence
While using both together can lower hemoglobin A1c without the additional weight gain, the risk of hypoglycemia increases as sulfonylureas force the body to make more insulin
