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DOI: 10.1111/obr.12436 Hiatt WR, Regensteiner JG, Creager MA, et al
Liraglutide is a GLP-1 receptor agonist used to manage weight and treat type 2 diabetes in adults
Researchers raise doses in animals until roughly 50% die, giving a crude measure of acute lethality that does not translate directly to human safety but gives context for risk margins
Expected weight change: An additional 2 to 4% of body weight over these four weeks, bringing cumulative loss to approximately 3 to 7%
The peptide requires refrigeration and careful handling due to its complex structure
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