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Preliminary results from the SURPASS-J-mono study in Japanese patients with T2D who were either therapy nave or on an antidiabetic monotherapy showed a head-to-head comparison of a tirzepatide treatment compared to therapy with the GLP-1RA dulaglutide at a dose of 0.75 mg (76)
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By applying a reverse translational approach that evaluates compounds with emerging clinical efficacy, we demonstrated that semaglutide, tirzepatide, and retatrutide blunt alcohol interoceptive/subjective effects, potentially clarifying a clinically meaningful mechanism
This factor is instrumental in the differentiation and maturation of goblet cells, signaling through the TRPA1-ERK pathway
Exendin-4 induces bone marrow stromal cells migration through bone marrow-Derived macrophages polarization via PKA-STAT3 signaling pathway
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