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Enhanced insulin secretion is glucose-dependent via potassium-sensitive adenosine triphosphate (K-ATP) channels mediating K + efflux, which close with a rise in intracellular ATP concentration from glucose metabolism
A baseline DEXA, repeated every three to six months on therapy
How GLP-1s are Currently Used That said, GLP-1s are currently being prescribed off-label to support fertility, particularly for those with PCOS
Semaglutide and Cardiovascular outcomes in patients with type 2 diabetes
Risk-Benefit Framework: When Providers Reassess Semaglutide Use Providers weigh maternal metabolic healthincluding gestational diabetes risk, pre-existing diabetes, and obesity-related complicationsagainst theoretical fetal exposure risk
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