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And its also a reminder: GLP-1s arent a miracle drug , but for some, they are a useful tool

Crucially, GLP-1 drugs have not been formally evaluated or approved by regulators as treatments for male infertility or hypogonadism

CagriSema targets two satiety pathways

Peripherally acting anti-obesity medicines with evidence for use in older adults Orlistat Weight loss trials None of the XENDOS trial participants were older adults, and hence the results from this study may not be applicable to an ageing population, although as the drug works peripherally there is no reason to suggest reduced efficacy or safety in elderly patients

Semaglutide with B12 has the same contraindications and potential side effects as semaglutide, including the risk of thyroid C-cell cancer (such as multiple endocrine neoplasia syndrome type 2), pancreatitis, hypoglycemia, and serious allergic reactions