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Goto et al
Direct and prolonged contact of copper with skin may result in electrochemical reactions to release copper ions, which are diffusible through the skin 2
PMID: 11382847
First: PI3K/Akt/mTOR, which drives protein synthesis, glucose uptake (via GLUT4 translocation), and anti-apoptotic signaling (particularly relevant in muscle and neuronal tissue)
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