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Its defining physicochemical feature is resistance to hydrolysis at low pH, unusual for a peptide of this length and attributed to a proline-rich, conformationally constrained backbone carrying three consecutive prolines plus a fourth at position eight
After an initial loading regimen of 1mg three times weekly for two weeks, maintenance therapy is typically 1mg every three months for life in conditions like pernicious anaemia, or every two months if neurological involvement was present
It is designed to function as a solvent or diluent for compatible compounds used in controlled laboratory research applications
The other option is for labs and researchers to buy from "research-use-only" vendors, who provide peptides with no prescription requirement, at a much lower cost
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