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In combination with metformin immediate-release and rosiglitazone, sitagliptin provided significant improvements in A1C, FPG, and 2-hour PPG compared to placebo with metformin immediate-release and rosiglitazone (Table 12) at Week 18
More serious but less common safety considerations observed across this drug class include a potential risk of pancreatitis, gallbladder-related conditions (such as gallstones/cholelithiasis), and based on animal studies a theoretical concern regarding thyroid C-cell tumours, though this has not been confirmed in human trials
Based on 100-unit insulin syringe (1 unit = 0.01 mL)
These risks are generally outweighed by the benefits when the drugs are used appropriately, but its important to consult with a healthcare provider before starting treatment
Heres the tricky part: coverage depends heavily on why youre taking it, your insurance provider, and even your specific plan
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