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Peripheral neuropathy, subacute combined degeneration of the spinal cord, or cognitive impairment indicate more advanced deficiency and generally require intensive treatment over extended periods

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Cell viability for GHK-Cu was previously investigated by Hairui et al, showing no significance difference between the control and the GHK-Cu treated group at the same concentrations and time points, implying the non-cytotoxic nature of GHK-Cu towards HaCaT 11

We dont exclude the possibility of a similar adaptation taking place behind the scenes, bringing out worse symptoms for a temporary period

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