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Its deficiency may lead to impaired wound healing, accelerated skin aging, and, in severe cases, scurvy (241, 243)

& Calva, E

Novo Nordisk presented these results at the European Association for the Study of Diabetes congress in September 2025 and used them to move cagrilintide into a dedicated phase 3 programme, RENEW

Bile acids may stimulate insulin secretion via activation of FXR and inhibition of ATP-dependent K + channels (172)

Restoring CRBP-1 could enhance retinol sensitivity and reduce ovarian cancer cell viability, potentially guiding personalized retinoid therapy for cancer patients (34)