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Lipid metabolism and the neonatal chicken
Presented for research literature review only Hoffmann C et al
33 Exenatide, also a GLP-1 receptor agonist, in a NASH mouse model showed an improvement of mitochondrial tricarboxylic acid cycle flux after a 8-week treatment, a significant decrease in insulin resistance, steatosis, hepatocyte lipotoxicity and hepatic triglyceride content as well as lower expression of hepatic lipogenic genes (Srebp1C, Cd36) and genes involved in inflammation and fibrosis
They can then adjust the treatment to get the best results
Un paciente con enfermedades del tracto gastrointestinal, antecedentes de pancreatitis, o alergias a los componentes del frmaco no es candidato
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