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Most importantly, this study demonstrates that compared to SGLT2i monotherapy, combination therapy with GLP-1RA and SGLT2i is associated with better clinical outcomes in patients with MASLD
Molecular architecture of the mouse nervous system
Despite promising preclinical results with inhibitors (e.g., ferrostatin-1) and gene therapies targeting GPX4/ACSL4, clinical translation faces critical barriers: the poorly defined temporal dynamics of ferroptosis post-stroke hinders therapeutic window optimization, and its interplay with necroptosis/pyroptosis requires clarification to guide combination therapies
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PubMed Central , Cleveland Clinic , Accessed 16 Feb
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