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Meningococcus primarily utilizes hemoglobin, transferrin, and lactoferrin as a source of iron, via specific outer membrane systems such as HmbR/HupAB for hemoglobin/heme and TbpA/TbpB and LbpA/LbpB for transferrin and lactoferrin, respectively
The growth hormone (GH)-axis of GH receptor/binding protein gene-disrupted and metallothionein-human GH-releasing hormone transgenic mice: hypothalamic neuropeptide and pituitary receptor expression in the absence and presence of GH feedback
The clinical study GeneBank was supported in part by P01 HL076491, P01 HL098055, R01 HL103931 and the Cleveland Clinic Foundation General Clinical Research Center of the Cleveland Clinic/Case Western Reserve University Clinical and Translational Science Award (1UL1RR024989)
Additional reported complications may involve gallbladder issues, pancreatitis, ileus (bowel paralysis), intestinal obstructions, and other gastrointestinal problems