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The damage caused by SAP to the vascular endothelium is manifested as the release of inflammatory mediators and leukocyte adhesion, increased vascular permeability, changes in blood flow shear stress, microthrombosis, and microcirculatory disorders

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59% Increase in total sleep time vs placebo (controlled study) 37 mo Normal sleep maintained after the last dose (chronic insomniacs) 1977 Year DSIP was first isolated 0 Documented dependence or withdrawal in clinical studies Studies show increased delta wave sleep Research on cortisol normalization Trials in chronic pain patients Demonstrated stress-reducing effects What to expect Your DSIP timeline