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Salvator H, Grassin-Delyle S, Brollo M, Couderc LJ, Abrial C, Victoni T, et al

Comprehensive diabetes care includes blood pressure control, lipid management, smoking cessation, and regular physical activityall of which contribute to both cardiovascular and cognitive health

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As such, it is not a surprise that many of the therapies proposed to target NSC loss of function and depletion may provide their beneficial effects through enhancing mitochondrial functionality to prevent excessive oxidative stress, including NAD + supplementation, metformin-induced mitochondrial biogenesis, and antioxidant supplementation (Khacho et al., 2019)