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Serum creatinine and blood urea nitrogen (BUN) assay Serum creatinine was determined using the Point creatinine assay (#C7548) according to the manufacturers directions
In human studies, long-term recreational ketamine use has been associated with structural brain changes, including reduced prefrontal gray matter volume and impaired white matter connectivity, which are potentially linked to chronic low-grade inflammation (Liao et al., 2011
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Avoid alcohol, which compounds the GI effects and stresses the liver during a period of active drug absorption
General Dose Management The most effective way to reduce side effect duration and severity is slow, controlled dose titration
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