According to NICE technology appraisal guidance (TA875) , semaglutide for weight management is recommended for adults with a BMI of 35 kg/m or greater, or 32.5 kg/m or greater for people from South Asian, Chinese, other Asian, Middle Eastern, Black African or African-Caribbean family backgrounds
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doi: 10.1093/ijnp/pyv030
Some people notice subtle changes within a few weeks, while others need several months to see significant improvements
Thus, excess concentrations of PUFA-containing phospholipids in membranes render them vulnerable to oxidative damage and subsequent ferroptosis [14, 15]