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Counteraction of GLP-1 effect on gastric emptying by co-infusion with prokinetic drug erythromycin during a liquid test meal diminished GLP-1s ability to decrease postprandial hyperglycemia in patients with T2DM (153)
Our results suggest that GGC can enter astrocytes and increase GSH levels and reduce the GSSG/GSH ratio, which in turn, attenuates intracellular oxidative stress and protect astrocytes from oligomeric A 40 -mediated oxidative stress and inflammatory response
They might also consider temporarily pausing dose escalation or adjusting your current dose if symptoms are significant
For some individuals, this triggers the stool reflex, causing diarrhea
![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/profile/Asfandyar-Sheikh/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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