Gastroparesis (Stomach Paralysis) Gastroparesis, commonly referred to as stomach paralysis, is a medical condition in which the stomach muscles no longer move food through the digestive tract at a normal rate
Alex Azar, former Secretary of the US Department of Health and Human Services, noted that there is little stigma around taking a statin to manage high cholesterol, but using a GLP-1 to help with weight loss can be perceived by some as taking the easy way out. Panelists emphasized that this perception, despite its inaccuracy, persists and may stand in the way of patients accessing these effective treatments or staying on them long-term
The STEP 4 trial showed that patients who stopped semaglutide after 68 weeks of treatment regained, on average, two-thirds of their lost weight within 52 weeks of discontinuation (Rubino et al., NEJM, 2021)
Call 911: After using the EpiPen, call 911 or your local emergency number
Small molecule GLP-1 agonists in the clinic Orally dosed small molecule receptor agonists of GLP-1R such as danuglipron, lotiglipron and orforglipron (Figure 1) have been discovered and have progressed into clinical trials