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However, this treatment paradigm demonstrates the acute reduction in apoB48 concentrations in the TRL fraction for 10 h post-injection (37%) compared to placebo controls with a significant decrease in apoB48 production rate, no change in fractional catabolic rate, and no changes in hepatic apoB100 levels were observed (Xiao et al., 2012)
Analytical Challenges in GLP-1 Development Despite their success, GLP-1 receptor agonists present significant analytical and development challenges
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