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Results Biallelic TEX44 variants disrupt sperm mitochondrial sheath Our investigation into the genetic underpinnings of asthenozoospermia involved a cohort of 800 infertile males using WES (Fig
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Glucagon receptor activation increases your body's resting metabolic rate (you burn more calories at rest) and promotes lipolysis (the breakdown of stored fat into fatty acids that can be used for energy)
Head-to-head data reinforce the signal: in SURPASS-2, tirzepatide produced greater weight loss than semaglutide up to 5.5 kg more at the top dose while lowering HbA1c by 2.30 points[2]. Its dual-receptor design is widely cited as why it outperforms single-pathway GLP-1 agonists[3]
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