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Slowing Gastric Emptying: GLP-1 slows gastric emptying, leading to a feeling of fullness (satiety)
Injectable routes carry a particular concern for immunogenicity from peptide aggregation and impurities, and FDA noted the available certificates of analysis for AOD-9604 bulk drug substances did not consistently control for impurities, aggregates, or microbial limits
But what about those zero-appetite days
Ozempic compared to Trulicity led to: lower blood sugars based on HbA1c by about 0.3%(-1.4% vs -1.1%)
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