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GPx enzyme activity was lower in patients with HF as compared to healthy controls when evaluating different compartments within the heart [64] as well as in their skeletal muscles [65]
In liver cancer cells, liraglutide-mediated inhibition of this pathway elevates intracellular transforming growth factor-1 (TGF-1) levels, which induces cell cycle arrest, autophagy, and senescence [64]
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