Pharmacol Biochem Behav 100:125129 Domingues-Faria C, Boirie Y, Walrand S (2017) Vitamin D and muscle trophicity
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If you have severe or persistent vomiting, cannot keep fluids down, or have intense abdominal pain, contact your clinician promptly rather than waiting
maintenance phase is the heavy draw 26 weeks 13 vials Standard Phase 2 duration 32 weeks 16 vials Phase 2 T2D study duration 68 weeks 30 vials REDEFINE 1 / REDEFINE 2 endpoint duration Peptide Vials (10 mg vial, 2.4 mg/week target) Each 10 mg vial covers about 4 weekly doses at 2.4 mg/week
Revised discontinuation assumptions: The discontinuation structure from the original CEA model was replaced with assumptions intended to more closely reflect treatment-continuation patterns observed in Japanese clinical practice