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Schedule a non-urgent but prompt appointment if: You notice new skin sensitivity that correlates temporally with a semaglutide dose increase

Brain imaging (fMRI) studies show muted reward-circuit activation in people on GLP-1 drugs when exposed to alcohol-related cues

[3] If you require B12 supplementation and are concerned about skin effects, discuss preventive skincare strategies with your healthcare provider before starting treatment, and monitor your skin during the initial weeks of therapy