Rather than full cessation, some clinicians discuss the option of maintenance dosing, using a lower dose or less frequent injection schedule to sustain appetite regulation at a reduced cost or with fewer side effects
For Nrf2 this was expected since Nrf2-induced activation of the ARE is commonly associated with chemo-resistance 36,37,38
Do not escalate the dosage too quickly, as it can cause severe side effects
2004, doi: 10.1093/JN/134.3.489
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