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Studies: Muscle strength and hypertrophy: A meta-analysis published in the Journal of the International Society of Sports Nutrition found that creatine supplementation significantly improves strength and lean body mass in various populations
Metformin enhances mitophagy and mitochondrial function, contributing to improved glucose and lipid metabolism
Importantly, these body weight changes were not attributable to differences in food intake across the groups, as all treatments showed similar food consumption patterns in both lean and obese mice
Tatlican O et al
Oxidative stress also induces the stabilization of HIF-1, enhancing angiogenesis and metastasis [101]
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