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In addition, individuals using weight-loss injections are 4.22 more at risk of developing bowel obstruction and 3.67 more likely to have gastroparesis or stomach paralysis
During the first 48 weeks on tirzepatide, when nausea and vomiting are most pronounced, plasma levels of oral antidepressants can fluctuate unpredictably, increasing the risk of breakthrough depressive or anxiety symptoms
It is indicated for the treatment of adult patients with the following conditions: Metastatic colorectal cancer who have received prior treatment with fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapy, an anti-VEGF biological therapy, and if they have RAS wild-type, an anti-EGFR therapy
"Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes." Lancet Diabetes & Endocrinology, vol
Semaglutide (the active ingredient in Wegovy and Ozempic) and especially Tirzepatide (the active ingredient in Zepbound and Mounjaro), which acts on both GLP-1 and another hormone called GIP, have shown higher average weight loss percentages
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