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Current studies are focusing on the ability of growth factors to protect in vitro cultured embryos from the detrimental effects of ROS such as apoptosis
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Treatment with EGCG could delay the outbreak or progression of ALS through changes in intracellular signals, increases survival signals (like PI3-K and Akt) and reduces death signals (like GKS-3, cytosolic cytochrome c, activated caspase-3 and cleaved poly ADP-ribose polymerase) (Levites et al., 2002
doi:10.2147/CMAR.S300495 11
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