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MedlinePlus warns that intramuscular injection site selection is important because you do not want to hit a nerve or blood vessel

I would say [the researchers] provide good evidence that the balance is shifting

doi:10.1016/S0140-6736(21)01751-7 Dutta D, Nagendra L, Harish BG, et al

Common side effects reported with retatrutide include: Nausea, vomiting, and diarrhoea (most frequent, particularly during dose escalation) Decreased appetite Constipation Injection site reactions Mild increases in heart rate Cagrilintide has demonstrated a generally well-tolerated profile, with gastrointestinal symptoms also being the most commonly reported adverse effects

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