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Subjects who developed NOD in the 3 years after statin initiation were identified and recruited, with diabetes defined as two or more of the following diagnostic elements: (1) FG 126 mg/dL, (2) diabetes ICD9 code, and/or (3) prescription of a glucose lowering drug (Supplementary Data 2)

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The results and data interpretations of the endpoint fluorescences were independently validated by electrophoretic mobility shift assays (Fig