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Finally, a pooled analysis of RCTs and open-label phase III studies showed that once-weekly exenatide reduced albuminuria 26% (95% CI%: 39.5 to 10%) compared with comparators (Van Der Aart-Van Der Beek et al., 2020)
This includes elevated LDL cholesterol, elevated triglycerides, or low HDL cholesterol
A Google Trends study published in the National Library of Medicine found a significant and growing public interest in GLP-1 agonists between 2023 and 2024
Additionally, evidence from a meta-analysis confirmed its effectiveness in promoting weight loss among individuals with overweight or obesity without diabetes [73]
Currently, only two RCTs have evaluated the efficacy of liraglutide at the approved dosage of 3.0 mg/day for the therapy of obesity
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