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Brown E, Wilding JPH, Barber TM, Alam U, Cuthbertson DJ (2019) Weight loss variability with SGLT2 inhibitors and GLP-1 receptor agonists in type 2 diabetes mellitus and obesity: mechanistic possibilities
JCSM Rapid Communications, 3(1), 2537
Figure 8: Atherosclerosis causes artery thickening (tunica intima hyperplasia) and clot formation by platelets
The Pathway: The hypothalamus releases GHRH (stimulating) or somatostatin (inhibiting)
Additional studies have reported that elevated brain iron levels lead to increased expression of programmed death ligand-1 (PD-L1) within the neurovascular unit
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