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[10] [11] It's important to understand that GLP-1 medications are initiated at a low dose and gradually increased over several weeks to minimise gastrointestinal side effects such as nausea and vomiting

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L-Carnitine is a common food supplement and naturally occurs in red meat

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ECUR-506, the companys lead investigational candidate, uses two adeno-associated virus (AAV) vectors: one carrying an ARCUS nuclease component to create a defined insertion site at a genomic safe harbor, and another delivering a functional copy of the OTC gene for targeted insertion