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Animal studies have demonstrated that GLP-1 RAs reduce the self-administration of alcohol, opioid, nicotine, and cocaine that effects are believed to be mediated through interactions with the mesolimbic dopamine system

And if cost or eligibility is a barrier, the right thing to do is talk to your GP or a healthcare professional rather than turning to an unproven alternative. Ian Budd, Prescribing Pharmacist at Chemist4U Alternatives to GLP-1 patches If you're looking for a safe, effective, and clinically approved weight loss treatment, here are the options you should consider

After removing three duplicates, a total of two articles were screened

The biggest factor is the reduction GLP-1 coverage, Arkoosh said

First-line options include polyethylene glycol 3350 (17 g daily) or a stimulant laxative such as senna