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In the wake of the success of GLP-1s, drug companies are scrambling to develop, test, and bring to market more behavior-supporting drugs

New Evidence on GLP-1 Receptor Agonists and Acute Pancreatitis Risk Exciting findings just published in The American Journal of Gastroenterology address a long-standing safety concern around GLP-1 receptor agonists (GLP-1 RAs) in type 2 diabetes: A multicenter, real-world analysis of more than 40,000 matched patients using the TriNetX network showed no increased risk of acute pancreatitis in GLP-1 RA users compared to non-users

Mark Fendrick.

We recommend gradual titration starting low and increasing slowly to improve tolerability

Emerging evidence suggests GLP-1 therapies like Semaglutide may positively influence this process