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Eli Lilly is also not far behind and is expected to submit its FDA application by the end of this year/early next year
Larger trials are needed before the effect sizes in current literature should be taken as definitive
Instead, it activates the GH secretagogue receptor 1a (GHSR1a), the same receptor that the natural hormone ghrelin binds to
Furthermore, while MACE included mortality attributed specifically to cardiac causes, the broader definition of mortality within MAKE did not allow for precise attribution to renal causes due to the limitations of diagnostic coding
A., Johnson, J
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