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The enzyme plays a more crucial role of inhibiting lipid peroxidation process, and therefore protects cells from oxidative stress.25 According to Morn and Cortzar, there are at least eight GPx enzymes in human, GPx1GPx8

Similarly, lactylation of NOP2/Sun RNA methyltransferase 2 enhances its catalytic activity and stabilizes GCLC mRNA via m5C modifications, leading to increased intracellular GSH levels and ferroptosis resistance in gastric cancer cells (121)

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ACT-AD Trial: Phase 2 Failure The ACT-AD phase 2 trial enrolled Alzheimer's patients and tested fosgonimeton efficacy on cognitive decline

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