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Sitagliptin and Metformin Coadministration in Patients with Type 2 Diabetes Inadequately Controlled on Diet and Exercise A total of 1091 patients with type 2 diabetes and inadequate glycemic control on diet and exercise participated in a 24-week, randomized, double-blind, placebo-controlled factorial study designed to assess the efficacy of sitagliptin and metformin coadministration
Is there clinical evidence behind these claims, or is this another case of compounding pharmacies bundling ingredients to justify premium pricing
As extensively described elsewhere [for a review, see Although a systematic review selects articles by PRISM, JBI, PICOS, or Cochrane, the present review uses keywords and free-text words in multiple databases
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Consistent benefit was seen across age and sex in subgroup analyses, with the strongest effect seen among older adults and women."Despite limitations such as residual confounding, the findings remain robust and suggest GLP-1 RAs could redefine T2DM-related dementia prevention strategies, warranting further randomized controlled trials to confirm these results," the authors write.Abstract/Full Text.Sign up for our weekly HealthDay newsletter
