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[6] Release of GST-A1 as an indication of cellular necrosis [edit] Increases in serum and urinary GST-A1 have been found in association with hepatocyte and renal proximal tubular necrosis respectively, and have potential for monitoring injury to these tissues

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That said, they are upfront about this cost increase which is what matters most in my eyes

Molecular mechanisms of heat shock factor 1 regulation