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An orally active allosteric GLP-1 receptor agonist is neuroprotective in cellular and rodent models of stroke

Dose microdosing strategies Microdosing tirzepatide has gained attention as an approach that uses lower doses more frequently to maintain steadier blood levels and reduce side effects

According to a news release, participants who did not receive tirzepatide experienced worse outcomes over time, with lower event-free survival. They said the participants who didnt take tirzepatide also faced a 54% higher risk of hospitalization for acute heart failure

N Engl J Med 355(23):24272443

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