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Intrahepatic natural killer T cell populations are increased in human hepatic steatosis
Incidence and distribution of argininosuccinate synthetase deficiency in human cancers: a method for identifying cancers sensitive to arginine deprivation
Dihexa is not a conventional peptide but a peptidomimetic a small molecule (~504 Da) designed to mimic peptide binding activity while resisting enzymatic degradation
Nave CD4 + T cells live in lymphoid organs and it is unlikely that inflammatory macrophages regulate the fate decisions of such T cells prior to their differentiation into memory/effector cells
Preclinical rodent studies support effects on angiogenesis, endothelial function, and nitric-oxide-related signaling, though these effects are reproducible in animals but not yet validated in humans
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